Dailydave mailing list archives
Re: The Source
From: Katie M <k8ek8e () gmail com>
Date: Fri, 1 Nov 2013 18:29:46 -0700
It's a matter of focus, and how soon we decide to do so for the purpose described in the initial pondering. The way genotyping is generally done is this: 0. Researcher chooses an expressed trait or disease for which they'd like to locate the genes responsible. 1. Researcher gathers a population of several families that express the trait or develop the disease with relative frequency. 2. Samples are gathered from both affected and unaffected family members and sequenced, looking for patterns to narrow down the gene or likely many genes responsible for the target trait/disease. 3. More work is done to analyze the patterns, because genes are ultimately just blueprints for proteins. Proteins have different functions in living cells. So differences in protein structure alter their functions, causing or contributing to the expressed trait or disease. So if I were to guess, we could do it if we chose to inside of a decade, but it would require a lot of focus. Katie Sent from my Windows Phone From: dan () geer org Sent: 11/1/2013 6:19 PM To: Katie M Cc: dailydave () lists immunityinc com Subject: Re: [Dailydave] The Source <skipping quoting your message> Katie, please make a prediction of time-scale until something of this sort would be possible. How much lead time do we have? Is a breakthrough conceivable, or is it a steady uphill grind? Sequencing was once unimaginably hard; now it is dirt cheap and growing incredibly fast. And portable. Give us some educated guesses, please. --dan _______________________________________________ Dailydave mailing list Dailydave () lists immunityinc com https://lists.immunityinc.com/mailman/listinfo/dailydave
Current thread:
- The Source Dave Aitel (Oct 31)
- Re: The Source Ali-Reza Anghaie (Nov 01)
- Re: The Source yersinia (Nov 01)
- <Possible follow-ups>
- Re: The Source Katie M (Nov 01)
- Re: The Source dan (Nov 04)
- Re: The Source Katie M (Nov 04)